|
KMID : 0361720050160040317
|
|
Korean Journal of perinatology
2005 Volume.16 No. 4 p.317 ~ p.321
|
|
|
Neonatal Lupus Erythematosus Manifests as Pancytopenia and Mildly Abnormal Liver Functions
|
|
Lee Seung-Min
Son Dong-Woo
Jeon In-Sang
Ham Soon-Shik
|
|
|
Abstract
|
|
|
|
Neonatal lupus erythematosus (NLE) is an uncommon passive autoimmune disease in which there is a transplacental passage of anti-Ro or anti-La maternal autoantibodies. The cutaneous lupus lesions are commonly observed and usually resolve spontaneously. The cardiac involvement which sometimes needs the permanent pacemaker, however, is the most clinically significant manifestation of NLE. In addition, the hepatic and hematologic abnormalities are observed in approximately 10% of infants with NLE. Therefore, in the way of the evaluation of hematologic disorders in neonate, NLE should be included. We present a case of NLE in an infant born to a mother with anti-Ro, and he had skin rash, pancytopenia and mildly abnormal liver functions without cardiac manifestation.
|
|
|
KEYWORD
|
|
|
Neonatal Lupus erythematosus, Pancytopenia, Anti-Ro antibody
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|